Reflecting on your practice problem and proposed research interventions what major biomedical principles as listed

Reflecting on your practice problem and proposed research interventions what major biomedical principles (as listed below) are involved?  Why is this principle important?  

Practice Problems ( DIABETES MELLITUS ) IT IS VERY IMPORTANT THAT YOU  REVIEW THE LAST ASSIGNMENT DID IT REGARDING ETHICAL CONSIDERETIONS.

I have provided a brief description of the biomedical ethical principles  There are many derivatives of these principles.  

4 major biomedical principles:

Autonomy: generally meaning the patient has the ethical right to make decisions and act on them.  Autonomy is acting with intentionality, understanding, and without influence.   (Autonomy vs paternalism).  

Non-Maleficence: Acting with the intention of doing no harm.  In medical care (or nursing care) it is the adage “first do no harm”. 

Beneficence: Acting with the intention of doing good/helping

Justice: There are various theories of justice: Justice involves the equitable distribution of resources. and has several different arguments that can be used in decision making. These include: each individual is treated equally; each according to one’s means/needs, each according to merit or contribution, each according to what society needs.